SynName: Anti -SSH1, NT (SSH1, KIAA1298, SSH1L, Protein phosphatase Slingshot homolog 1, SSH-like protein 1); *Specificity: HumanImmunogen: SSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the N-terminal region of human SSH1.; *Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.; *Accession#: NP_009842.1; NM_001178631.1; P38353; *Description: The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).; *Uniprot Summary: Function: Part of the Ssh1 complex, which probably is the major component of a channel-forming translocon complex that may function exclusively in the cotranslational pathway of protein endoplasmic reticulum (ER) import. Ref.7Subunit structure: Component of the heterotrimeric Ssh1 complex, which is composed of SSH1, SBH2 and SSS1.Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Miscellaneous: Present with 704 molecules/cell in log phase SD medium.Sequence similarities: Belongs to the SecY/SEC61-alpha family.
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